Subjects: Nursing >> Nursing submitted time 2023-05-12
Abstract： Objective To investigate the related symptoms, symptom cluster and influencing factors among patients with gynecological cancer during chemotherapy. Methods A total of 430 inpatients with gynecological cancer treated by chemotherapy were investigated by using the General Information Questionnaire and Chinese version of M. D. Anderson Symptom Inventory (MDASI). Results There were many symptoms in gynecological cancer patients during chemotherapy. The top three symptom incidence were vomiting (91.86%), drowsiness (90.70%) and fatigue (90.00%). The top three incidence of symptomatic distress were walking (76.74%), interpersonal (76.30%) and emotion (72.79%). Four symptom groups were extracted by exploratory factor analysis, namely emotional symptom cluster, disease symptom cluster, fatigue symptom cluster and digestive tract symptom cluster. Multivariate stepwise regression analysis showed that metastasis, family monthly income, recurrence, expected hospital stay, number of chemotherapy, chemotherapy regimen, tumor staging and work status were the influencing factors of symptoms. Conclusion There are many symptoms in gynecological cancer patients during chemotherapy. Clinical nurses should start from the point of view of symptom cluster, and provide effective symptoms management measures for patients, to improve their quality of life.
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Subjects: Nursing >> Nursing submitted time 2022-10-21
Abstract： Objective To investigate the effect of predictive nursing strategies on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome. Methods? Totally 40 patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome were randomly divided into the observation group and control group, with 20 cases in each group. Routing nursing management including posture nursing, oral care, psychological care and nursing of adverse reactions was carried out in the control group. In the observation group, a special nursing team was set up to enhance the predictive nursing interventions such as nutrition support, prevention of infection and hemorrhage, and so on. The side effects of azacitidine therapy were observed analyzed. Results The incidence of adverse reactions in the observation group was significantly lower than that in the control group (10.00% vs. 45.00%, P＜0.05). Conclusion? For those patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome, the predictive nursing is potentially effective to reduce the incidence of adverse drug reactions.
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